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Arf Suppresses Hepatic Vascular Neoplasia in a Carcinogen-Exposed Murine Model
Hepatic haemangiosarcoma is a deadly malignancy whose aetiology remains poorly understood. Inactivation of the CDKN2A locus, which houses the ARF and p16(INK4a) tumour suppressor genes, is a common event in haemangiosarcoma patients, but the precise role of ARF in vascular tumourigenesis is unknown....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871210/ https://ncbi.nlm.nih.gov/pubmed/22430984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4024 |
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