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ARF Inhibits the Growth and Malignant Progression of Non-Small Cell Lung Carcinoma

Non-small cell lung carcinoma (NSCLC) is among the deadliest of human cancers. The CDKN2A locus, which houses the INK4a and ARF tumor suppressor genes, is frequently altered in NSCLC. However, the specific role of ARF in pulmonary tumorigenesis remains unclear. KRAS and other oncogenes induce the ex...

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Hlavní autoři: Busch, Stephanie E, Moser, Russell D, Gurley, Kay E, Kelly-Spratt, Karen S, Liggitt, H Denny, Kemp, Christopher J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839253/
https://ncbi.nlm.nih.gov/pubmed/23752194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.208
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