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Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans
Roundabout 1 (Robo1) is the cognate receptor for secreted axon guidance molecule, Slits, which function to direct cellular migration during neuronal development and angiogenesis. The Slit2–Robo1 signaling is modulated by heparan sulfate, a sulfated linear polysaccharide that is abundantly expressed...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871176/ https://ncbi.nlm.nih.gov/pubmed/23994753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2013.08.018 |
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