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Characterization of the interaction between Robo1 and heparin and other glycosaminoglycans

Roundabout 1 (Robo1) is the cognate receptor for secreted axon guidance molecule, Slits, which function to direct cellular migration during neuronal development and angiogenesis. The Slit2–Robo1 signaling is modulated by heparan sulfate, a sulfated linear polysaccharide that is abundantly expressed...

詳細記述

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書誌詳細
主要な著者: Zhang, Fuming, Moniz, Heather A., Walcott, Benjamin, Moremen, Kelley W., Linhardt, Robert J., Wang, Lianchun
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871176/
https://ncbi.nlm.nih.gov/pubmed/23994753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2013.08.018
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