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Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing.

The mouse mutant jimpy carries an X chromosome-linked recessive gene defect that affects the formation of myelin in the central nervous system. To understand the molecular basis of the jimpy mutation, we have examined the expression of mRNAs encoding myelin proteolipid protein (PLP). PLP mRNAs were...

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Detaylı Bibliyografya
Asıl Yazarlar: Nave, K A, Lai, C, Bloom, F E, Milner, R J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1986
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC387116/
https://ncbi.nlm.nih.gov/pubmed/3466187
Etiketler: Etiketle
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