Myosin Heads Are Displaced from Actin Filaments in the In Situ Beating Rat Heart in Early Diabetes

Diabetes is independently associated with a specific cardiomyopathy, characterized by impaired cardiac muscle relaxation and force development. Using synchrotron radiation small-angle x-ray scattering, this study investigated in the in situ heart and in real-time whether changes in cross-bridge disp...

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Autors principals: Jenkins, Mathew J., Pearson, James T., Schwenke, Daryl O., Edgley, Amanda J., Sonobe, Takashi, Fujii, Yutaka, Ishibashi-Ueda, Hatsue, Kelly, Darren J., Yagi, Naoto, Shirai, Mikiyasu
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2013
Matèries:
Molecular Machines, Motors, and Nanoscale Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870813/
https://ncbi.nlm.nih.gov/pubmed/23473489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.037
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