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Lower and upper stem–single-stranded RNA junctions together determine the Drosha cleavage site
Microprocessor [Drosha–DGCR8 (DiGeorge syndrome critical region gene 8) complex] processing of primary microRNA (pri-miRNA) is the critical first step in miRNA biogenesis, but how the Drosha cleavage site is determined has been unclear. Previous models proposed that the Drosha–DGCR8 complex measures...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870748/ https://ncbi.nlm.nih.gov/pubmed/24297910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311639110 |
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