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Collective polarization model for gradient sensing via Dachsous-Fat intercellular signaling

Dachsous-Fat signaling via the Hippo pathway influences proliferation during Drosophila development, and some of its mammalian homologs are tumor suppressors, highlighting its role as a universal growth regulator. The Fat/Hippo pathway responds to morphogen gradients and influences the in-plane pola...

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Detalhes bibliográficos
Main Authors: Mani, Madhav, Goyal, Sidhartha, Irvine, Kenneth D., Shraiman, Boris I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870718/
https://ncbi.nlm.nih.gov/pubmed/24282293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307459110
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