Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions

The cadherins Fat and Dachsous regulate cell polarity and proliferation via their heterophilic interactions at intercellular junctions. Their ectodomains are unusually large because of repetitive extracellular cadherin (EC) domains, which raises the question of how they fit in regular intercellular...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Tsukasaki, Yoshikazu, Miyazaki, Naoyuki, Matsumoto, Atsushi, Nagae, Shigenori, Yonemura, Shigenobu, Tanoue, Takuji, Iwasaki, Kenji, Takeichi, Masatoshi
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4234546/
https://ncbi.nlm.nih.gov/pubmed/25355906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418990111
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