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Crystallographic insights into sodium-channel modulation by the β4 subunit
Voltage-gated sodium (Na(v)) channels are embedded in a multicomponent membrane signaling complex that plays a crucial role in cellular excitability. Although the mechanism remains unclear, β-subunits modify Na(v) channel function and cause debilitating disorders when mutated. While investigating wh...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870679/ https://ncbi.nlm.nih.gov/pubmed/24297919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314557110 |
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