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Cellular distribution of copper to superoxide dismutase involves scaffolding by membranes

Efficient delivery of copper ions to specific intracellular targets requires copper chaperones that acquire metal cargo through unknown mechanisms. Here we demonstrate that the human and yeast copper chaperones (CCS) for superoxide dismutase 1 (SOD1), long thought to exclusively reside in the cytoso...

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Detalhes bibliográficos
Main Authors: Pope, Christopher R., De Feo, Christopher J., Unger, Vinzenz M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870662/
https://ncbi.nlm.nih.gov/pubmed/24297923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309820110
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