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Cellular distribution of copper to superoxide dismutase involves scaffolding by membranes

Efficient delivery of copper ions to specific intracellular targets requires copper chaperones that acquire metal cargo through unknown mechanisms. Here we demonstrate that the human and yeast copper chaperones (CCS) for superoxide dismutase 1 (SOD1), long thought to exclusively reside in the cytoso...

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Detalles Bibliográficos
Main Authors: Pope, Christopher R., De Feo, Christopher J., Unger, Vinzenz M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870662/
https://ncbi.nlm.nih.gov/pubmed/24297923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309820110
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