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Ric-8 Proteins Are Molecular Chaperones That Direct Nascent G Protein α Subunit Membrane Association

Ric-8A (resistance to inhibitors of cholinesterase 8A) and Ric-8B are guanine nucleotide exchange factors that enhance different heterotrimeric guanine nucleotide–binding protein (G protein) signaling pathways by unknown mechanisms. Because transgenic disruption of Ric-8A or Ric-8B in mice caused ea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gabay, Meital, Pinter, Mary E., Wright, Forrest A., Chan, PuiYee, Murphy, Andrew J., Valenzuela, David M., Yancopoulos, George D., Tall, Gregory G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870195/
https://ncbi.nlm.nih.gov/pubmed/22114146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002223
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