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Structure–activity relationships for biodistribution, pharmacokinetics, and excretion of atomically precise nanoclusters in a murine model()

The absorption, distribution, metabolism and excretion (ADME) and pharmacokinetic (PK) properties of inorganic nanoparticles with hydrodynamic diameters between 2 and 20 nm are presently unpredictable. It is unclear whether unpredictable in vivo properties and effects arise from a subset of molecule...

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Detalhes bibliográficos
Main Authors: Wong, O. Andrea, Hansen, Ryan J., Ni, Thomas W., Heinecke, Christine L., Compel, W. Scott, Gustafson, Daniel L., Ackerson, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870010/
https://ncbi.nlm.nih.gov/pubmed/24057086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3nr03121g
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