Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer

The class Ia ribonucleotide reductase (RNR) from Escherichia coli (Ec) employs a free-radical mechanism, which involves bidirectional translocation of a radical equivalent or “hole” over a distance of ∼35 Å from the stable diferric/tyrosyl-radical (Y(122)•) cofactor in the β subunit to cysteine 439...

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Detalhes bibliográficos
Main Authors: Wörsdörfer, Bigna, Conner, Denise A., Yokoyama, Kenichi, Livada, Jovan, Seyedsayamdost, Mohammad, Jiang, Wei, Silakov, Alexey, Stubbe, JoAnne, Bollinger, J. Martin, Krebs, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869997/
https://ncbi.nlm.nih.gov/pubmed/23676140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja401342s
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