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Identification of two anti-parallel beta-sheet conformations in the solution structure of murine epidermal growth factor by proton magnetic resonance.

Epidermal growth factor (EGF) is a small mitogenic protein. Proteins with sequence homology with EGF or with its membrane-bound protein receptor have been proposed to play a role in oncogenesis. This report describes solution NMR data that provide evidence that the solution conformation of murine EG...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Montelione, G T, Wüthrich, K, Nice, E C, Burgess, A W, Scheraga, H A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1986
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3490668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.22.8594
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