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EGFRvIII Mediates Hepatocellular Carcinoma Cell Invasion by Promoting S100 Calcium Binding Protein A11 Expression

Epidermal growth factor receptor (EGFR) is frequently aberrantly expressed in cancer, and abnormal signalling downstream of this receptor contributes to tumour growth. EGFR variant III (EGFRvIII) is the most commonly altered form of EGFR and contains a truncated ligand-binding domain. Aberrant signa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Luo, Xiaoying, Xie, Hailong, Long, Xiaolan, Zhou, Min, Xu, Zhibin, Shi, Bizhi, Jiang, Hua, Li, Zonghai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869758/
https://ncbi.nlm.nih.gov/pubmed/24376686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083332
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