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Maintenance of Basal Levels of Autophagy in Huntington’s Disease Mouse Models Displaying Metabolic Dysfunction

Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by an expanded polyglutamine repeat in the huntingtin protein. Neuropathology in the basal ganglia and in the cerebral cortex has been linked to the motor and cognitive symptoms whereas recent work has suggested that the hypothal...

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Detalhes bibliográficos
Main Authors: Baldo, Barbara, Soylu, Rana, Petersén, Åsa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869748/
https://ncbi.nlm.nih.gov/pubmed/24376631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083050
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