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Antibody–peptide–MHC fusion conjugates target non-cognate T cells to kill tumour cells
Attempts to generate robust anti-tumour cytotoxic T lymphocyte (CTL) responses using immunotherapy are frequently thwarted by exhaustion and anergy of CTL recruited to tumour. One strategy to overcome this is to retarget a population of virus-specific CTL to kill tumour cells. Here, we describe a pr...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer-Verlag
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869625/ https://ncbi.nlm.nih.gov/pubmed/23604105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1408-8 |
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