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Formation of muconaldehyde, an open-ring metabolite of benzene, in mouse liver microsomes: an additional pathway for toxic metabolites.

It has been proposed that a ring-opened form may be responsible for the toxicity of benzene. The present studies demonstrate that incubation of [14C]benzene with liver microsomes (obtained from male CD-1 mice treated with benzene) in the presence of NADPH results in the formation of a ring-opened pr...

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Библиографические подробности
Главные авторы: Latriano, L, Goldstein, B D, Witz, G
Формат: Artigo
Язык:Inglês
Опубликовано: 1986
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC386927/
https://ncbi.nlm.nih.gov/pubmed/3464956
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