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Metabolism and toxicity of trans,trans-muconaldehyde, an open-ring microsomal metabolite of benzene.

We have previously hypothesized that ring-opened metabolites may play an important role in benzene toxicity. In this paper we review recent work related to this hypothesis. trans,trans-Muconaldehyde (TTM), a six-carbon diene dialdehyde, was shown by our laboratory to be a microsomal metabolite of be...

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Detalhes bibliográficos
Main Authors: Witz, G, Latriano, L, Goldstein, B D
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568136/
https://ncbi.nlm.nih.gov/pubmed/2676497
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