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Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies.

We investigated the immunochemical and molecular characteristics of murine monoclonal rheumatoid factors. Study of the fine specificity of 20 monoclonal rheumatoid factor antibodies shows a wide degree of heterogeneity. However, many express an interstrain cross-reactive idiotype. We show that our r...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Manheimer-Lory, A J, Monestier, M, Bellon, B, Alt, F W, Bona, C A
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1986
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3095832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.21.8293
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