Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies.

We investigated the immunochemical and molecular characteristics of murine monoclonal rheumatoid factors. Study of the fine specificity of 20 monoclonal rheumatoid factor antibodies shows a wide degree of heterogeneity. However, many express an interstrain cross-reactive idiotype. We show that our r...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Manheimer-Lory, A J, Monestier, M, Bellon, B, Alt, F W, Bona, C A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386914/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3095832/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.21.8293
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