Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies.

We investigated the immunochemical and molecular characteristics of murine monoclonal rheumatoid factors. Study of the fine specificity of 20 monoclonal rheumatoid factor antibodies shows a wide degree of heterogeneity. However, many express an interstrain cross-reactive idiotype. We show that our r...

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Autores principales: Manheimer-Lory, A J, Monestier, M, Bellon, B, Alt, F W, Bona, C A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1986
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC386914/
https://ncbi.nlm.nih.gov/pubmed/3095832
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