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Fine specificity, idiotypy, and nature of cloned heavy-chain variable region genes of murine monoclonal rheumatoid factor antibodies.

We investigated the immunochemical and molecular characteristics of murine monoclonal rheumatoid factors. Study of the fine specificity of 20 monoclonal rheumatoid factor antibodies shows a wide degree of heterogeneity. However, many express an interstrain cross-reactive idiotype. We show that our r...

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Détails bibliographiques
Auteurs principaux: Manheimer-Lory, A J, Monestier, M, Bellon, B, Alt, F W, Bona, C A
Format: Artigo
Langue:Inglês
Publié: 1986
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC386914/
https://ncbi.nlm.nih.gov/pubmed/3095832
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