Progression-Free Survival (PFS) as a Surrogate Endpoint of Overall Survival (OS) in Patients with Metastatic Renal Cell Carcinoma (mRCC)

PURPOSE: To investigate the dependence between PFS and OS in mRCC patients and to explore whether PFS can be used as an intermediate endpoint of OS in this patient population. PATIENTS AND METHODS: A total of 1,381 patients from two prospective phase III trials (CALGB 90206 and AVOREN) of interferon...

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Bibliografische gegevens
Hoofdauteurs: Halabi, Susan, Rini, Brian, Escudier, Bernard, Stadler, Walter M., Small, Eric J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869105/
https://ncbi.nlm.nih.gov/pubmed/24347384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28221
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