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Replacing sulfa drugs with novel DHPS inhibitors

More research effort needs to be invested in antimicrobial drug development to address the increasing threat of multidrug-resistant organisms. The enzyme DHPS has been a validated drug target for over 70 years as the target for the highly successful sulfa drugs. The use of sulfa drugs has been compr...

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Autori principali: Hammoudeh, Dalia I, Zhao, Ying, White, Stephen W, Lee, Richard E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869102/
https://ncbi.nlm.nih.gov/pubmed/23859210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.97
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