The Antiallergic Mast Cell Stabilizers Lodoxamide and Bufrolin as the First High and Equipotent Agonists of Human and Rat GPR35

Lack of high potency agonists has restricted analysis of the G protein–coupled receptor GPR35. Moreover, marked variation in potency and/or affinity of current ligands between human and rodent orthologs of GPR35 has limited their productive use in rodent models of physiology. Based on the reported m...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: MacKenzie, Amanda E., Caltabiano, Gianluigi, Kent, Toby C., Jenkins, Laura, McCallum, Jennifer E., Hudson, Brian D., Nicklin, Stuart A., Fawcett, Lindsay, Markwick, Rachel, Charlton, Steven J., Milligan, Graeme
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2014
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868900/
https://ncbi.nlm.nih.gov/pubmed/24113750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.089482
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