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Antagonists of GPR35 Display High Species Ortholog Selectivity and Varying Modes of Action
Variation in pharmacology and function of ligands at species orthologs can be a confounding feature in understanding the biology and role of poorly characterized receptors. Substantial selectivity in potency of a number of GPR35 agonists has previously been demonstrated between human and rat ortholo...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3500541/ https://ncbi.nlm.nih.gov/pubmed/22967846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.198945 |
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