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AKT3 controls mitochondrial biogenesis and autophagy via regulation of the major nuclear export protein CRM-1
Our previous work has shown that Akt3 is required for mitochondrial biogenesis in primary human endothelial cells (ECs) and in Akt3-null mice; Akt3 affects subcellular localization of peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1α), the master regulator of mitochondrial biogenesi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868834/ https://ncbi.nlm.nih.gov/pubmed/24081905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-235382 |
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