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Transient Receptor Potential Channel 6 (TRPC6) Protects Podocytes during Complement-mediated Glomerular Disease

Gain-of-function mutations in the calcium channel TRPC6 lead to autosomal dominant focal segmental glomerulosclerosis and podocyte expression of TRPC6 is increased in some acquired human glomerular diseases, particularly in membranous nephropathy. These observations led to the hypothesis that TRPC6...

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Bibliografiske detaljer
Main Authors: Kistler, Andreas D., Singh, Geetika, Altintas, Mehmet M., Yu, Hao, Fernandez, Isabel C., Gu, Changkyu, Wilson, Cory, Srivastava, Sandeep Kumar, Dietrich, Alexander, Walz, Katherina, Kerjaschki, Dontscho, Ruiz, Phillip, Dryer, Stuart, Sever, Sanja, Dinda, Amit K., Faul, Christian, Reiser, Jochen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868772/
https://ncbi.nlm.nih.gov/pubmed/24194522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.488122
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