Podocyte-Specific Overexpression of Wild Type or Mutant Trpc6 in Mice Is Sufficient to Cause Glomerular Disease

Mutations in the TRPC6 calcium channel (Transient receptor potential channel 6) gene have been associated with familiar forms of Focal and Segmental Glomerulosclerosis (FSGS) affecting children and adults. In addition, acquired glomerular diseases are associated with increased expression levels of T...

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Autors principals: Krall, Paola, Canales, Cesar P., Kairath, Pamela, Carmona-Mora, Paulina, Molina, Jessica, Carpio, J. Daniel, Ruiz, Phillip, Mezzano, Sergio A., Li, Jing, Wei, Changli, Reiser, Jochen, Young, Juan I., Walz, Katherina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942896/
https://ncbi.nlm.nih.gov/pubmed/20877463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012859
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