Characterization of a Trpc6 Transgenic Mouse Associated with Early Onset FSGS

RATIONALE: Mutations in Transient Receptor Potential Channel 6 (TRPC6) gene are associated with autosomal dominant focal and segmental glomerulosclerosis (FSGS). The majority of the identified mutations affect the ion channel function. Since calcium channels are promising candidate drug targets, the...

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Bibliographic Details
Published in:Br J Med Med Res
Main Authors: Canales, Cesar P., Krall, Paola, Kairath, Pamela, Perez, Irene C., Fragoso, Miryam A., Carmona-Mora, Paulina, Ruiz, Phillip, Reiser, Jochen, Young, Juan I., Walz, Katherina
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130885/
https://ncbi.nlm.nih.gov/pubmed/34012910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9734/bjmmr/2015/12493
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