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Characterization of a Trpc6 Transgenic Mouse Associated with Early Onset FSGS

RATIONALE: Mutations in Transient Receptor Potential Channel 6 (TRPC6) gene are associated with autosomal dominant focal and segmental glomerulosclerosis (FSGS). The majority of the identified mutations affect the ion channel function. Since calcium channels are promising candidate drug targets, the...

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Detalhes bibliográficos
Publicado no:Br J Med Med Res
Main Authors: Canales, Cesar P., Krall, Paola, Kairath, Pamela, Perez, Irene C., Fragoso, Miryam A., Carmona-Mora, Paulina, Ruiz, Phillip, Reiser, Jochen, Young, Juan I., Walz, Katherina
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130885/
https://ncbi.nlm.nih.gov/pubmed/34012910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9734/bjmmr/2015/12493
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