Combinatorial PD-1 Blockade and CD137 Activation Has Therapeutic Efficacy in Murine Cancer Models and Synergizes with Cisplatin

There is an urgent need for improved therapy for advanced ovarian carcinoma, which may be met by administering immune-modulatory monoclonal antibodies (mAbs) to generate a tumor-destructive immune response. Using the ID8 mouse ovarian cancer model, we investigated the therapeutic efficacy of various...

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Main Authors: Wei, Huafeng, Zhao, Likun, Li, Wei, Fan, Kexing, Qian, Weizhu, Hou, Sheng, Wang, Hao, Dai, Min, Hellstrom, Ingegerd, Hellstrom, Karl Erik, Guo, Yajun
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868659/
https://ncbi.nlm.nih.gov/pubmed/24367702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084927
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