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Global analysis of phosphorylation and ubiquitylation crosstalk in protein degradation

Crosstalk between different types of post-translational modifications (PTMs) on the same protein molecule adds specificity and combinatorial logic to signal processing, but has not been characterized on a large-scale basis. Here, we developed two methods to identify protein isoforms that are both ph...

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Detalhes bibliográficos
Main Authors: Swaney, Danielle L., Beltrao, Pedro, Starita, Lea, Guo, Ailan, Rush, John, Fields, Stanley, Krogan, Nevan J., Villén, Judit
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868471/
https://ncbi.nlm.nih.gov/pubmed/23749301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2519
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