Coordinate to Guard: Crosstalk of Phosphorylation, Sumoylation, and Ubiquitylation in DNA Damage Response

Small ubiquitin-like modifier-1/2/3 (SUMO-1/2/3) and ubiquitin share similar structure and utilize analogous machinery for protein lysine conjugation. Although sumoylation and ubiquitylation have distinct functions, they are often tightly associated with each other to fine-tune protein fate in trans...

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Bibliographic Details
Main Authors: Kuo, Ching-Ying, Shieh, Christine, Cai, Fei, Ann, David Kong
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355946/
https://ncbi.nlm.nih.gov/pubmed/22649771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2011.00061
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