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Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter

Mechanisms of regulation of mitochondrial metabolism in trypanosomes are not completely understood. Here we present evidence that the Trypanosoma brucei mitochondrial calcium uniporter (TbMCU) is essential for regulation of mitochondrial bioenergetics, autophagy, and cell death, even in the bloodstr...

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Hlavní autoři: Huang, Guozhong, Vercesi, Anibal E., Docampo, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868461/
https://ncbi.nlm.nih.gov/pubmed/24305511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3865
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