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Essential regulation of cell bioenergetics in Trypanosoma brucei by the mitochondrial calcium uniporter

Mechanisms of regulation of mitochondrial metabolism in trypanosomes are not completely understood. Here we present evidence that the Trypanosoma brucei mitochondrial calcium uniporter (TbMCU) is essential for regulation of mitochondrial bioenergetics, autophagy, and cell death, even in the bloodstr...

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Detalhes bibliográficos
Main Authors: Huang, Guozhong, Vercesi, Anibal E., Docampo, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868461/
https://ncbi.nlm.nih.gov/pubmed/24305511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3865
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