Harnessing of the Nucleosome Remodeling Deacetylase complex controls lymphocyte development and prevents leukemogenesis

Cell fate decisions depend on the interplay between chromatin regulators and transcription factors. Here we show that activity of the Mi-2β nucleosome remodeling and deacetylase (NuRD) complex was controlled by the Ikaros family of lymphoid-lineage determining proteins. Ikaros, an integral component...

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Bibliografische gegevens
Hoofdauteurs: Zhang, Jiangwen, Jackson, Audrey F., Naito, Taku, Dose, Marei, Seavitt, John, Liu, Feifei, Heller, Elizabeth J., Kashiwagi, Mariko, Yoshida, Toshimi, Gounari, Fotini, Petrie, Howard T., Georgopoulos, Katia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868219/
https://ncbi.nlm.nih.gov/pubmed/22080921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2150
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