Knockdown of Glyoxalase 1 Mimics Diabetic Nephropathy in Nondiabetic Mice

Differences in susceptibility to diabetic nephropathy (DN) between mouse strains with identical levels of hyperglycemia correlate with renal levels of oxidative stress, shown previously to play a central role in the pathogenesis of DN. Susceptibility to DN appears to be genetically determined, but t...

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Bibliografiska uppgifter
Huvudupphovsmän: Giacco, Ferdinando, Du, Xueliang, D’Agati, Vivette D., Milne, Ross, Sui, Guangzhi, Geoffrion, Michele, Brownlee, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2014
Ämnen:
Complications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868051/
https://ncbi.nlm.nih.gov/pubmed/24062246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0316
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