Population-based analysis of Alzheimer’s disease risk alleles implicates genetic interactions

BACKGROUND: Reported odds ratios and population attributable fractions (PAF) for late-onset Alzheimer’s disease (LOAD) risk loci (BIN1, ABCA7, CR1, MS4A4E, CD2AP, PICALM, MS4A6A, CD33, and CLU) come from clinically ascertained samples. Little is known about the combined PAF for these LOAD risk allel...

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主要な著者: Ebbert, Mark T. W., Ridge, Perry G., Wilson, Andrew R., Sharp, Aaron R., Bailey, Matthew, Norton, Maria C., Tschanz, JoAnn T., Munger, Ronald G., Corcoran, Christopher D., Kauwe, John S. K.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867586/
https://ncbi.nlm.nih.gov/pubmed/23954108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.07.008
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