Mitochondrial Genomic Analysis of Late Onset Alzheimer’s Disease Reveals Protective Haplogroups H6A1A/H6A1B: The Cache County Study on Memory in Aging

BACKGROUND: Alzheimer’s disease (AD) is the most common cause of dementia and AD risk clusters within families. Part of the familial aggregation of AD is accounted for by excess maternal vs. paternal inheritance, a pattern consistent with mitochondrial inheritance. The role of specific mitochondrial...

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Main Authors: Ridge, Perry G., Maxwell, Taylor J., Corcoran, Christopher D., Norton, Maria C., Tschanz, JoAnn T., O’Brien, Elizabeth, Kerber, Richard A., Cawthon, Richard M., Munger, Ronald G., Kauwe, John S. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444479/
https://ncbi.nlm.nih.gov/pubmed/23028804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045134
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