Dysregulation of Leptin Signaling in Alzheimer Disease: Evidence for Neuronal Leptin Resistance

Leptin signaling has received considerable attention in the Alzheimer disease (AD) field. Within the past decade, the peptide hormone has been demonstrated to attenuate tau hyperphosphorylation in neuronal cells and to be modulated by amyloid-β. Moreover, a role in neuroprotection and neurogenesis w...

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Main Authors: Bonda, David J., Stone, Jeremy G., Torres, Sandy L., Siedlak, Sandra L., Perry, George, Kryscio, Richard, Jicha, Gregory, Casadesus, Gemma, Smith, Mark A., Zhu, Xiongwei, Lee, Hyoung-gon
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867585/
https://ncbi.nlm.nih.gov/pubmed/23895348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12380
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