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Dysregulation of Leptin Signaling in Alzheimer Disease: Evidence for Neuronal Leptin Resistance
Leptin signaling has received considerable attention in the Alzheimer disease (AD) field. Within the past decade, the peptide hormone has been demonstrated to attenuate tau hyperphosphorylation in neuronal cells and to be modulated by amyloid-β. Moreover, a role in neuroprotection and neurogenesis w...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3867585/ https://ncbi.nlm.nih.gov/pubmed/23895348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12380 |
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