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Dysregulation of Leptin Signaling in Alzheimer Disease: Evidence for Neuronal Leptin Resistance

Leptin signaling has received considerable attention in the Alzheimer disease (AD) field. Within the past decade, the peptide hormone has been demonstrated to attenuate tau hyperphosphorylation in neuronal cells and to be modulated by amyloid-β. Moreover, a role in neuroprotection and neurogenesis w...

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Autors principals: Bonda, David J., Stone, Jeremy G., Torres, Sandy L., Siedlak, Sandra L., Perry, George, Kryscio, Richard, Jicha, Gregory, Casadesus, Gemma, Smith, Mark A., Zhu, Xiongwei, Lee, Hyoung-gon
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867585/
https://ncbi.nlm.nih.gov/pubmed/23895348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12380
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