Dysregulation of Leptin Signaling in Alzheimer Disease: Evidence for Neuronal Leptin Resistance

Leptin signaling has received considerable attention in the Alzheimer disease (AD) field. Within the past decade, the peptide hormone has been demonstrated to attenuate tau hyperphosphorylation in neuronal cells and to be modulated by amyloid-β. Moreover, a role in neuroprotection and neurogenesis w...

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Bibliografiske detaljer
Main Authors: Bonda, David J., Stone, Jeremy G., Torres, Sandy L., Siedlak, Sandra L., Perry, George, Kryscio, Richard, Jicha, Gregory, Casadesus, Gemma, Smith, Mark A., Zhu, Xiongwei, Lee, Hyoung-gon
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867585/
https://ncbi.nlm.nih.gov/pubmed/23895348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12380
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