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Dysregulation of Leptin Signaling in Alzheimer Disease: Evidence for Neuronal Leptin Resistance

Leptin signaling has received considerable attention in the Alzheimer disease (AD) field. Within the past decade, the peptide hormone has been demonstrated to attenuate tau hyperphosphorylation in neuronal cells and to be modulated by amyloid-β. Moreover, a role in neuroprotection and neurogenesis w...

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Detalhes bibliográficos
Main Authors: Bonda, David J., Stone, Jeremy G., Torres, Sandy L., Siedlak, Sandra L., Perry, George, Kryscio, Richard, Jicha, Gregory, Casadesus, Gemma, Smith, Mark A., Zhu, Xiongwei, Lee, Hyoung-gon
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3867585/
https://ncbi.nlm.nih.gov/pubmed/23895348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12380
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