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Post-transcriptional modifications modulate conformational dynamics in human U2–U6 snRNA complex

The spliceosome catalyzes precursor-mRNA splicing in all eukaryotes. It consists of over 100 proteins and five small nuclear RNAs (snRNAs), including U2 and U6 snRNAs, which are essential for catalysis. Human and yeast snRNAs share structural similarities despite the fact that human snRNAs contain n...

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Detalhes bibliográficos
Main Authors: Karunatilaka, Krishanthi S., Rueda, David
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866641/
https://ncbi.nlm.nih.gov/pubmed/24243115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.041806.113
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