XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway

BACKGROUND: Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. The present treatment including surgery, chemotherapy and radiation, which have only 40% long-term cure rates, and usually cause tumor recurrence. Thus, looking for new effective and less toxic therapies has imp...

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Bibliografiske detaljer
Main Authors:	Tian, Xiao-Hong, Hou, Wei-Jian, Fang, Yan, Fan, Jun, Tong, Hao, Bai, Shu-Ling, Chen, Qu, Xu, He, Li, Yan
Format:	Artigo
Sprog:	Inglês
Udgivet:	BioMed Central 2013
Fag:	Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3866601/ https://ncbi.nlm.nih.gov/pubmed/24308762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-100
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XAV939, a tankyrase 1 inhibitior, promotes cell apoptosis in neuroblastoma cell lines by inhibiting Wnt/β-catenin signaling pathway

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