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The N-terminal region of influenza virus polymerase PB1 adjacent to the PA binding site is involved in replication but not transcription of the viral genome

The influenza virus genome forms viral ribonucleoprotein (vRNP) complexes with nucleoprotein and viral RNA-dependent RNA polymerases (RdRp), PB1, PB2, and PA subunits. The vRNP complex catalyzes both genome replication and transcription reactions. PB1 contains the motifs highly conserved among RdRps...

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Bibliografski detalji
Glavni autori: Binh, Nguyen Trong, Wakai, Chitose, Kawaguchi, Atsushi, Nagata, Kyosuke
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866587/
https://ncbi.nlm.nih.gov/pubmed/24391632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2013.00398
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