Recognition of Cap Structure by Influenza B Virus RNA Polymerase Is Less Dependent on the Methyl Residue than Recognition by Influenza A Virus Polymerase

The cap-dependent endonuclease activity of the influenza virus RNA-dependent RNA polymerase cleaves host mRNAs to produce capped RNA fragments for primers to initiate viral mRNA synthesis. The influenza A virus (FluA) cap-dependent endonuclease preferentially recognizes the cap1 structure (m(7)GpppN...

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Bibliographic Details
Main Authors: Wakai, Chitose, Iwama, Minako, Mizumoto, Kiyohisa, Nagata, Kyosuke
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147943/
https://ncbi.nlm.nih.gov/pubmed/21593178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02375-10
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