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SPIC: A novel similarity metric for comparing transcription factor binding site motifs based on information contents

BACKGROUND: Discovering transcription factor binding sites (TFBS) is one of primary challenges to decipher complex gene regulatory networks encrypted in a genome. A set of short DNA sequences identified by a transcription factor (TF) is known as a motif, which can be expressed accurately in matrix f...

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Detalles Bibliográficos
Autores principales: Zhang, Shaoqiang, Zhou, Xiguo, Du, Chuanbin, Su, Zhengchang
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866262/
https://ncbi.nlm.nih.gov/pubmed/24564945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-7-S2-S14
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