Aspirin Use, 8q24 Single Nucleotide Polymorphism rs6983267, and Colorectal Cancer According to CTNNB1 Alterations

BACKGROUND: Regular aspirin use reduces the risk for colorectal cancer (CRC), possibly through inhibition of WNT/cadherin-associated protein β1 (CTNNB1 or β-catenin) signaling. The single nucleotide polymorphism (SNP) rs6983267 on chromosome 8q24 is a CRC susceptibility locus that affects binding ac...

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Bibliografski detalji
Glavni autori: Nan, Hongmei, Morikawa, Teppei, Suuriniemi, Miia, Imamura, Yu, Werner, Lillian, Kuchiba, Aya, Yamauchi, Mai, Hunter, David J., Kraft, Peter, Giovannucci, Edward L., Fuchs, Charles S., Ogino, Shuji, Freedman, Matthew L., Chan, Andrew T.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866156/
https://ncbi.nlm.nih.gov/pubmed/24317174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt331
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