GIP plus xenin-25 indirectly increases pancreatic polypeptide release in humans with and without type 2 diabetes mellitus

Xenin-25 (Xen) is a 25-amino acid neurotensin-related peptide that activates neurotensin receptor-1 (NTSR1). We previously showed that Xen increases the effect of glucose-dependent insulinotropic polypeptide (GIP) on insulin release 1) in hyperglycemic mice via a cholinergic relay in the periphery i...

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Bibliografiske detaljer
Main Authors: Chowdhury, Sara, Wang, Songyan, Patterson, Bruce W., Reeds, Dominic N., Wice, Burton M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866049/
https://ncbi.nlm.nih.gov/pubmed/24183983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2013.10.003
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